SCHEMBL28857397

SCHEMBL28857397

O=C(c1ccccc1)c1ccccc1-c1cccc(Br)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
AKR1C3 P42330 2/20 0.46
NR4A1 P22736 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPT P10636 3/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.41
ALDH1A1 P00352 2/20 0.41
PRNP P04156 1/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29093033 0.86 AKR1C3 (0.52) TP53AKR1C3NR4A1MAPTGAA
SCHEMBL28072751 0.84 AKR1C3 (0.53) TP53AKR1C3CYP2C8CYP2C9MAPT
SCHEMBL27729040 0.83 TSHR (0.52) AKR1C3NR4A1CYP2C8CYP2C9MAPT
SCHEMBL934811 0.80 AKR1C3 (0.67) AKR1C3NR4A1CYP2C8CYP2C9MAPT
SCHEMBL27803960 0.78 AKR1C3 (0.53) AKR1C3NR4A1CYP2C8CYP2C9MAPT
SCHEMBL1666433 0.77 AKR1C3 (0.57) AKR1C3NR4A1CYP2C8CYP2C9MAPT
SCHEMBL29913321 0.77 AKR1C3 (0.61) TP53AKR1C3MAPTGAAKMT2A
SCHEMBL723657 0.77 AKR1C3 (0.61) TP53AKR1C3MAPTGAAKMT2A
SCHEMBL14831119 0.76 AKR1C3 (0.52) TP53AKR1C3MAPTGAAKMT2A
SCHEMBL29683548 0.75 AKR1C3 (0.55) TP53AKR1C3NR4A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160272-B Nitrogen-containing compound, and electronic element and electronic device using same 陕西莱特光电材料股份有限公司 2023-10-31 CN disclosed
CN-115160272-A Nitrogen-containing compound, and electronic element and electronic device using same 陕西莱特光电材料股份有限公司 2022-10-11 CN disclosed