Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414068 | 0.88 | KMT2A (0.76) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10414069 | 0.88 | KMT2A (0.76) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4778536 | 0.85 | KMT2A (0.81) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11688124 | 0.85 | KMT2A (0.81) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4778528 | 0.85 | KMT2A (0.81) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14047083 | 0.84 | KMT2A (0.69) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14271668 | 0.83 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7534268 | 0.83 | KMT2A (0.68) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7534264 | 0.83 | KMT2A (0.68) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10501798 | 0.80 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107805200-A | Method for preparing α -alkyl- β -ketoester compounds | 西华大学 | 2018-03-16 | — | — | CN | disclosed |