Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167982 | 0.89 | KMT2A (0.80) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL9803295 | 0.89 | KMT2A (0.80) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL10787479 | 0.89 | KMT2A (0.80) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL4509654 | 0.87 | KMT2A (0.77) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL27933717 | 0.86 | NR4A2 (0.65) | KMT2ANR4A2AKR1C3NR1H4MRGPRX4 | |
| SCHEMBL6932542 | 0.86 | KMT2A (0.75) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL920108 | 0.85 | MAOB (0.60) | KMT2ARAB9A | |
| SCHEMBL7843724 | 0.85 | KMT2A (0.51) | KMT2ANR4A2PRSS1 | |
| SCHEMBL8517907 | 0.84 | KMT2A (0.73) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 | |
| SCHEMBL19665046 | 0.84 | KMT2A (0.73) | KMT2ANR4A2AKR1C3PLA2G4BNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-108084077-A | A kind of synthetic method of zafirlukast intermediate | 江汉大学 | 2018-05-29 | — | — | CN | disclosed |