SCHEMBL2885909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12975617	0.92	GRM1 (0.64)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL2885912	0.89	GRM1 (0.60)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL2885670	0.89	GRM1 (0.80)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL12975622	0.88	GRM1 (0.59)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL2888899	0.87	GRM1 (0.65)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL12975631	0.87	GRM1 (0.60)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL2891310	0.86	GRM1 (0.63)	GRM1GRM5HRH1TMEM97SLC6A15
	SCHEMBL2885508	0.85	GRM1 (0.72)	GRM1GRM5HRH1TMEM97
	SCHEMBL2890753	0.84	GRM1 (0.61)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL2888978	0.84	GRM1 (0.69)	GRM1GRM5HRH1TMEM97TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.