6',7'-Epoxybergamottin

6',7'-Epoxybergamottin

SCHEMBL28859461

CC(=CCOc1c2ccoc2cc2oc(=O)ccc12)CCC1OC1(C)C

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.74
ALDH1A1 P00352 4/20 0.72
KDM4E B2RXH2 3/20 0.72
BACE1 P56817 3/20 0.72
TDP1 Q9NUW8 2/20 0.72
CYP2E1 P05181 1/20 0.72
CYP2D6 P10635 1/20 0.72
CYP2C9 P11712 1/20 0.72
TSHR P16473 1/20 0.72
CYP2B6 P20813 1/20 0.72
CYP3A5 P20815 1/20 0.72
CYP2C19 P33261 1/20 0.72
MEN1 O00255 1/20 0.72
MAPT P10636 1/20 0.72
HPGD P15428 1/20 0.72
MAPK1 P28482 1/20 0.72
KMT2A Q03164 1/20 0.72
HSD17B10 Q99714 1/20 0.72
LMNA P02545 2/20 0.69
POLB P06746 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6',7'-Epoxybergamottin SCHEMBL29419949 1.00 CYP3A4 (0.74) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714668 0.87 CYP3A4 (0.59) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714872 0.87 CYP3A4 (0.59) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714673 0.87 CYP3A4 (0.59) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13895385 0.85 CYP3A4 (0.58) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714671 0.84 CYP3A4 (0.58) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13973667 0.84 CYP3A4 (0.56) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714670 0.84 CYP3A4 (0.58) CYP3A4ALDH1A1KDM4EBACE1TDP1
SCHEMBL13714664 0.84 CYP3A4 (0.58) CYP3A4ALDH1A1KDM4EBACE1TDP1
Bergamottin SCHEMBL569529 0.84 CYP3A4 (1.00) CYP3A4ALDH1A1KDM4EBACE1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874199-B Method for simultaneously preparing epoxy orange peel oleosin and epoxy bergamotin 集美大学 2024-04-09 CN disclosed
CN-114874199-A Method for simultaneously preparing epoxy auraptene and epoxy bergamottin 集美大学 2022-08-09 CN disclosed