SCHEMBL28859550

SCHEMBL28859550

c1ccc(COc2ccc([C@@H]3C[C@H]3NCc3cccnc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 19/20 0.75
MAOA P21397 13/20 0.75
MAOB P27338 12/20 0.75
MAPK1 P28482 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28859551 1.00 KDM1A (0.75) KDM1AMAOAMAOBMAPK1
SCHEMBL528284 0.89 KDM1A (0.77) KDM1AMAOAMAOB
SCHEMBL528285 0.89 KDM1A (0.77) KDM1AMAOAMAOB
SCHEMBL238697 0.88 KDM1A (0.92) KDM1AMAOAMAOB
SCHEMBL238698 0.88 KDM1A (0.92) KDM1AMAOAMAOB
SCHEMBL28212117 0.86 KDM1A (0.78) KDM1AMAOAMAOB
SCHEMBL28212118 0.86 KDM1A (0.78) KDM1AMAOAMAOB
SCHEMBL238346 0.86 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL238347 0.86 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL13263166 0.86 KDM1A (1.00) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849611-A biomarkers related to L SD1 inhibitors and uses thereof 奥瑞泽恩基因组学股份有限公司 2018-03-27 CN disclosed