Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL4304790 | 0.94 | TSHR (0.64) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL1164653 | 0.94 | TSHR (0.64) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL28092825 | 0.94 | TSHR (0.64) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL34552 | 0.94 | — | — | |
| SCHEMBL2167689 | 0.94 | — | — | |
| Fumaric Acid SCHEMBL9170981 | 0.94 | TSHR (0.64) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL14359 | 0.94 | — | — | |
| SCHEMBL5156781 | 0.90 | — | — | |
| SCHEMBL3442849 | 0.90 | — | — | |
| SCHEMBL9364041 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101976-A | A kind of N-terminal special human DNA mismatch repair protein MLH1 polypeptides and its preparation method for antibody | 南京瑞姆生物科技有限公司 | 2018-06-01 | — | — | CN | disclosed |