Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 14/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22918752 | 0.78 | KIT (0.56) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29614113 | 0.78 | KIT (0.56) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29868714 | 0.78 | KIT (0.51) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29615418 | 0.78 | KIT (0.51) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29615575 | 0.74 | KIT (0.81) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29614180 | 0.71 | KIT (0.51) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29709020 | 0.71 | KIT (0.51) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL22918645 | 0.71 | KIT (0.51) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL29615536 | 0.71 | KIT (0.79) | KITLCKCSF1RPDGFRBPDGFRA | |
| SCHEMBL28862465 | 0.71 | KIT (0.79) | KITLCKCSF1RPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |