Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.88 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.88 |
| ▸ | CASP7 | P55210 | 3/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.88 |
| ▸ | VDR | P11473 | 3/20 | 0.88 |
| ▸ | TP53 | P04637 | 2/20 | 0.88 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.88 |
| ▸ | BLM | P54132 | 2/20 | 0.88 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.88 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 2/20 | 0.88 |
| ▸ | USP2 | O75604 | 2/20 | 0.88 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.88 |
| ▸ | MDM4 | O15151 | 1/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.88 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithocholic Acid SCHEMBL21841344 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL20829087 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL22479406 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL24567422 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL22079173 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL23923735 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL24001494 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL24001453 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL22894393 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 | |
| Lithocholic Acid SCHEMBL22871939 | 0.94 | GPBAR1 (1.00) | GPBAR1EPHA2CASP7HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2449488-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES Life Sciences AG (AT) | 2012-05-09 | — | — | EP | disclosed |
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |