Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27966357 | 0.96 | — | — | |
| Pyridine SCHEMBL28185628 | 0.93 | TSHR (0.64) | TSHRNAPRTTDP1NOTUM | |
| Pyridine SCHEMBL3627909 | 0.93 | — | — | |
| Pyridine SCHEMBL1066444 | 0.93 | TSHR (0.75) | TSHRNAPRTTDP1NOTUM | |
| Pyridine SCHEMBL27737222 | 0.93 | TSHR (0.75) | TSHRNAPRTTDP1NOTUM | |
| Pyridine SCHEMBL27752357 | 0.89 | — | — | |
| Pyridine SCHEMBL28012077 | 0.86 | TSHR (0.64) | TSHRNAPRTTDP1NOTUM | |
| Pyridine SCHEMBL10752757 | 0.84 | — | — | |
| Pyridine SCHEMBL29517174 | 0.84 | TSHR (0.90) | TSHRNAPRTTDP1NOTUM | |
| Pyridine SCHEMBL563923 | 0.84 | TSHR (0.90) | TSHRNAPRTTDP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108541346-A | Imaging sensor including global electronic shutter | 因维萨热技术公司 | 2018-09-14 | — | — | CN | disclosed |