Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KIT | P10721 | 5/20 | 0.54 |
| ▸ | BRAF | P15056 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923610 | 0.84 | NR1H2 (0.72) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL273351 | 0.82 | NR1H2 (1.00) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL29493475 | 0.82 | NR1H2 (1.00) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL9609582 | 0.81 | NR1H2 (0.68) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL9610930 | 0.81 | NR1H2 (0.68) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL13772028 | 0.81 | NR1H2 (0.64) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL15545229 | 0.80 | KDM4E (0.49) | NR1H2KDM4EALDH1A1POLB | |
| SCHEMBL15371491 | 0.80 | NR1H2 (0.67) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL19853099 | 0.80 | NR1H2 (0.67) | NR1H2KDM4EALDH1A1POLBKIT | |
| SCHEMBL19085530 | 0.79 | NR1H2 (0.65) | NR1H2KDM4EALDH1A1POLBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197168-A | Preparation method of flumatinib and analogues thereof | 江苏豪森药业集团有限公司 | 2022-10-18 | — | — | CN | disclosed |