Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL36964 | 0.97 | TP53 (0.79) | TP53MAPTTSHRSLC7A5RNPEP | |
| Lactic Acid SCHEMBL9312897 | 0.93 | TP53 (0.73) | TP53MAPTTSHRSLC7A5RNPEP | |
| Lactic Acid SCHEMBL28099744 | 0.89 | — | — | |
| Lactic Acid SCHEMBL5825768 | 0.89 | — | — | |
| Lactic Acid SCHEMBL29204818 | 0.86 | — | — | |
| Lactic Acid SCHEMBL28724201 | 0.86 | — | — | |
| Lactic Acid SCHEMBL11154522 | 0.86 | TP53 (0.85) | TP53TSHRALDH1A1LMNASLC7A5 | |
| Lactic Acid SCHEMBL20523337 | 0.86 | — | — | |
| Lactic Acid SCHEMBL1995735 | 0.86 | TP53 (0.85) | TP53TSHRALDH1A1LMNASLC7A5 | |
| Lactic Acid SCHEMBL5931031 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197370-A | High-strength high-nanocellulose-content flexible conductive composite material and preparation method and application thereof | 南京林业大学 | 2022-10-18 | — | — | CN | disclosed |