Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872374 | 0.89 | DPP4 (1.00) | DPP4KMT2AHTR7FOLH1PDCD1 | |
| SCHEMBL469051 | 0.89 | DPP4 (1.00) | DPP4KMT2AHTR7FOLH1PDCD1 | |
| Hydrochloric Acid SCHEMBL4776720 | 0.87 | DPP4 (0.95) | DPP4KMT2AHTR7FOLH1PDCD1 | |
| Bicarbonate SCHEMBL27817695 | 0.86 | DPP4 (0.83) | DPP4KMT2AHTR7FOLH1PDCD1 | |
| SCHEMBL2981250 | 0.85 | DPP4 (0.91) | DPP4KMT2AHTR7FOLH1PDCD1 | |
| SCHEMBL27670027 | 0.81 | DPP4 (0.83) | DPP4KMT2AHTR7PDCD1CD274 | |
| Hydrogen Sulfide SCHEMBL27639875 | 0.79 | DPP4 (0.79) | DPP4KMT2AHTR7PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL29502692 | 0.79 | DPP4 (0.79) | DPP4KMT2AHTR7PDCD1CD274 | |
| SCHEMBL3288611 | 0.78 | DPP4 (0.69) | DPP4HSD17B10PNMTMAPK1CYP11B1 | |
| Water SCHEMBL27607122 | 0.76 | DPP4 (0.67) | DPP4KMT2AHTR7PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473429-A | ROR gamma modulators | 领先制药控股公司 | 2018-08-31 | — | — | CN | disclosed |