Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406208 | 0.89 | POLB (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7289985 | 0.89 | POLB (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL1701604 | 0.89 | POLB (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL15438887 | 0.89 | POLB (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL15447586 | 0.89 | POLB (0.49) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1375057 | 0.87 | POLB (0.48) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1374314 | 0.87 | POLB (0.48) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL28864626 | 0.81 | HSD17B10 (0.42) | ALDH1A1L3MBTL1RAB9ALMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL28864610 | 0.81 | HSD17B10 (0.42) | ALDH1A1L3MBTL1RAB9ALMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL28864675 | 0.81 | HSD17B10 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |