Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445770 | 0.81 | PLA2G10 (0.39) | PLA2G10PLA2G5NR1H2USP2SMN1; SMN2 | |
| SCHEMBL28864589 | 0.79 | PLA2G10 (0.38) | PLA2G10PLA2G5NR1H2USP2SMN1; SMN2 | |
| SCHEMBL28864553 | 0.79 | MEN1 (0.42) | PLA2G10PLA2G5SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28864578 | 0.79 | MEN1 (0.42) | PLA2G10PLA2G5SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13698842 | 0.79 | PLA2G10 (0.36) | PLA2G10PLA2G5NR1H2CCNT1CDK9 | |
| SCHEMBL28983818 | 0.79 | PLA2G10 (0.40) | PLA2G10PLA2G5NR1H2CCNT1CDK9 | |
| SCHEMBL25355009 | 0.79 | PLA2G10 (0.40) | PLA2G10PLA2G5NR1H2CCNT1CDK9 | |
| SCHEMBL28864559 | 0.78 | PIK3CD (0.41) | PLA2G10PLA2G5NR1H2USP2SMN1; SMN2 | |
| SCHEMBL22549567 | 0.77 | PLA2G10 (0.39) | PLA2G10PLA2G5NR1H2HTR4KDM4E | |
| SCHEMBL19687318 | 0.77 | PLA2G10 (0.39) | PLA2G10PLA2G5NR1H2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |