Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28865180 | 0.80 | MME (0.39) | TSHRTP53 | |
| SCHEMBL13334533 | 0.79 | TSHR (0.46) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL21959474 | 0.76 | CYP1A2 (0.56) | TSHRALDH1A1CYP3A4TP53ADRB2 | |
| SCHEMBL9498462 | 0.75 | CYP3A4 (0.42) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL242931 | 0.75 | CYP3A4 (0.42) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL2269394 | 0.75 | CYP3A4 (0.42) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL832850 | 0.75 | EPHX1 (0.48) | ALDH1A1MAOAEPHX1 | |
| SCHEMBL17550074 | 0.73 | TSHR (0.61) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL8696253 | 0.73 | TSHR (0.41) | TSHRGFERALDH1A1CYP3A4TDP1 | |
| SCHEMBL18152435 | 0.73 | PPARG (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705051-A | Tri- substituted oxazoline of 2,4,5- and its synthetic method | 湖南城市学院 | 2019-05-03 | — | — | CN | claimed |
| CN-109705051-A | Tri- substituted oxazoline of 2,4,5- and its synthetic method | 湖南城市学院 | 2019-05-03 | — | — | CN | disclosed |
| CN-104177298-B | Bis- substitution -4,5- dihydros -1H of 4,4--imidazoles -5- ketone, derivative and its synthetic method | 湘潭大学 | 2018-10-02 | — | — | CN | disclosed |