Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106078 | 1.00 | KCNH2 (0.39) | KCNH2EPHX1POLBHRH4HRH3 | |
| SCHEMBL28178790 | 0.90 | MAPK1 (0.41) | EPHX1MAPK1OPRK1SSTR4SLC6A1 | |
| SCHEMBL28615966 | 0.89 | EPHX1 (0.44) | EPHX1POLBSSTR1SSTR4GABRA5 | |
| SCHEMBL28249909 | 0.83 | EPHX1 (0.37) | KCNH2EPHX1POLBHRH4HRH3 | |
| SCHEMBL27886443 | 0.79 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL25206807 | 0.79 | SSTR4 (0.45) | SSTR1SSTR4 | |
| SCHEMBL27990542 | 0.76 | BTK (0.41) | EPHX1 | |
| SCHEMBL27805832 | 0.74 | GAA (0.42) | EPHX1 | |
| SCHEMBL28019745 | 0.74 | KDM1A (0.33) | EPHX1 | |
| SCHEMBL27891337 | 0.73 | EPHX1 (0.39) | KCNH2EPHX1POLBMAPK1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602770-A | Novel biphenol compound or its salt | 大鹏药品工业株式会社 | 2018-09-28 | — | — | CN | disclosed |