Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 11/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287861 | 1.00 | CAPN1 (0.71) | CAPN1ITGB1ITGA4 | |
| SCHEMBL298845 | 1.00 | CAPN1 (0.71) | CAPN1ITGB1ITGA4 | |
| SCHEMBL289791 | 1.00 | CAPN1 (0.71) | CAPN1ITGB1ITGA4 | |
| SCHEMBL299450 | 0.94 | CAPN1 (0.70) | CAPN1ITGB1ITGA4 | |
| SCHEMBL288173 | 0.94 | CAPN1 (0.70) | CAPN1ITGB1ITGA4 | |
| SCHEMBL289316 | 0.94 | CAPN1 (0.70) | CAPN1ITGB1ITGA4 | |
| SCHEMBL1612436 | 0.89 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL288617 | 0.89 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL288910 | 0.89 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL288113 | 0.87 | CAPN1 (0.74) | CAPN1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427429-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | Abbott GmbH & Co. KG (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128102-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-11-11 | — | — | WO | disclosed |