SCHEMBL2886579

SCHEMBL2886579

Clc1cc2c(c(Cl)c1Cl)Oc1ccccc1O2

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHR P35869 18/20 0.73
FLT1 P17948 1/20 0.42
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118871 0.87 AHR (0.86) AHRFLT1CYP3A4
SCHEMBL9579657 0.87 AHR (0.86) AHRFLT1CYP3A4
SCHEMBL5967950 0.87 AHR (0.86) AHRFLT1CYP3A4
SCHEMBL29353218 0.87 AHR (0.86) AHRFLT1CYP3A4
SCHEMBL29353294 0.85 AHR (1.00) AHRFLT1CYP3A4
SCHEMBL2885718 0.85 AHR (1.00) AHRFLT1CYP3A4
SCHEMBL30118867 0.84 AHR (0.82) AHRFLT1CYP3A4
SCHEMBL29353168 0.84 AHR (0.82) AHRFLT1CYP3A4
SCHEMBL2464142 0.84 AHR (0.82) AHRFLT1CYP3A4
SCHEMBL11458863 0.83 AHR (0.51) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811760-B2 Vector and method for detecting the change in transcription amount KABUSHIKI KAISHA TOSHIBA (JP) 2010-10-12 US disclosed
US-20080003596-A1 VECTOR AND METHOD FOR DETECTING THE CHANGE IN TRANSCRIPTION AMOUNT KABUSHIKI KAISHA TOSHIBA (JP) 2008-01-03 US disclosed
JP-2006180773-A NEW MICROORGANISM WITH DIOXIN DECOMPOSING POTENTIAL AND METHOD FOR DECOMPOSING DIOXIN KANSAI ELECTRIC POWER CO INC:THE 2006-07-13 JP disclosed
US-20050064576-A1 Methods for remediating materials contaminated with halogenated aromatic compounds RUTGERS, THE STATE UNIVERSITY 2005-03-24 US disclosed
US-20040169139-A1 Chemical monitoring method and apparatus, and incinerator HITACHI, LTD. 2004-09-02 US disclosed
US-6723286-B2 Chemical monitoring method and apparatus, and incinerator HITACHI, LTD. (JP) 2004-04-20 US disclosed
JP-2004097110-A METHOD FOR DECOMPOSING DIOXINS TO INORGANIC MATERIAL BY WHITE-ROT FUNGUS JAPAN SCIENCE & TECHNOLOGY CORP 2004-04-02 JP disclosed
US-6649910-B2 Analytical apparatus HITACHI, LTD. (JP) 2003-11-18 US disclosed
US-20030020013-A1 Analytical apparatus HITACHI, LTD. 2003-01-30 US disclosed
US-6483108-B1 Analytical apparatus HITACHI, LTD. (JP) 2002-11-19 US disclosed
US-20020110490-A1 Chemical monitoring method and apparatus, and incinerator HITACHI, LTD. 2002-08-15 US disclosed
US-20020048818-A1 Chemical monitoring method and apparatus, and incinerator HITACHI, LTD. 2002-04-25 US disclosed
US-5550311-A WATER POLLUTION CONTROL HPR CORPORATION (US) 1996-08-27 US disclosed
WO-1996024558-A1 METHOD AND APPARATUS FOR THERMAL DECOMPOSITION AND SEPARATION OF COMPONENTS WITHIN AN AQUEOUS STREAM HPR CORPORATION (US) 1996-08-15 WO disclosed
US-4238472-A DOUBLE ANTIBODY QUANTITATIVE ANALYSIS; EMULSIFICATION USING AN ETHYLENE OXIDE ALKYLPHENOL ADDUCT UNITED STATES OF AMERICA (US) 1980-12-09 US disclosed