Cloflucarban

Cloflucarban

SCHEMBL28866649

O=C(Nc1ccc(Cl)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1.O=C(Nc1ccc(Cl)cc1)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.80
EPHX1 P07099 2/20 0.74
EPHX2 P34913 2/20 0.74
MEN1 O00255 1/20 0.74
NPC1 O15118 1/20 0.74
LMNA P02545 1/20 0.74
ADORA3 P0DMS8 1/20 0.74
CHRM1 P11229 1/20 0.74
SLC6A2 P23975 1/20 0.74
PDE4A P27815 1/20 0.74
ADRA1A P35348 1/20 0.74
OPRM1 P35372 1/20 0.74
HTT P42858 1/20 0.74
KMT2A Q03164 1/20 0.74
PDE3A Q14432 1/20 0.74
NLRP3 Q96P20 1/20 0.74
CA1 P00915 3/20 0.66
CA2 P00918 3/20 0.66
CA7 P43166 3/20 0.66
CA9 Q16790 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cloflucarban SCHEMBL119821 0.96 KDR (0.88) KDREPHX1EPHX2MEN1NPC1
Cloflucarban SCHEMBL27537485 0.96 KDR (0.88) KDREPHX1EPHX2MEN1NPC1
SCHEMBL4548158 0.94 KDR (0.90) KDREPHX1EPHX2MEN1NPC1
SCHEMBL118026 0.89 KDR (1.00) KDRCA1CA2CA7CA9
SCHEMBL29364392 0.89 KDR (1.00) KDRCA1CA2CA7CA9
SCHEMBL10220062 0.87 KDR (0.88) KDREPHX1EPHX2CA1CA2
SCHEMBL162962 0.87 KDR (0.67) KDREPHX1EPHX2MEN1NPC1
Triclocarban SCHEMBL68658 0.86 MEN1 (1.00) EPHX1EPHX2MEN1NPC1LMNA
Triclocarban SCHEMBL30479188 0.86 MEN1 (1.00) EPHX1EPHX2MEN1NPC1LMNA
Triclocarban SCHEMBL4978963 0.86 MEN1 (1.00) EPHX1EPHX2MEN1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797234-B Mild antibiotic cleaning compositions 荷兰联合利华有限公司 2018-12-14 CN disclosed