Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561719 | 0.98 | HRH3 (0.54) | HRH3L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL26488889 | 0.98 | HRH3 (0.54) | HRH3L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL5946012 | 0.94 | HRH3 (0.46) | HRH3ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5251326 | 0.92 | HRH3 (0.50) | HRH3ALDH1A1CYP1A2CYP2D6KDM4E | |
| SCHEMBL15718696 | 0.89 | HRH3 (0.41) | HRH3ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL64778 | 0.85 | HRH3 (0.39) | HRH3L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL271825 | 0.83 | HRH3 (0.42) | HRH3L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL28110383 | 0.83 | HRH3 (0.42) | HRH3L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5544476 | 0.82 | CXCR4 (0.47) | HRH3MEN1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27805378 | 0.81 | CXCR4 (0.46) | HRH3MEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-A | 1- cyano-pyrolidin derivative as DUB inhibitor | 特殊治疗有限公司 | 2018-11-23 | — | — | CN | disclosed |