Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28066761 | 1.00 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL14562444 | 0.91 | HDAC1 (0.52) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Bicarbonate SCHEMBL10590002 | 0.91 | HDAC1 (0.52) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL11353075 | 0.88 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL11353114 | 0.88 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL4958826 | 0.86 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28129801 | 0.86 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Propionic Acid SCHEMBL28468420 | 0.86 | FFAR3 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Propionic Acid SCHEMBL406808 | 0.86 | FFAR3 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL29215809 | 0.86 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109401212-A | Polymer blend and heat-shrinkable film and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109401215-A | Polymer blend and non-woven fabrics and its preparation method and application | 中国石油化工股份有限公司 | 2019-03-01 | — | — | CN | disclosed |