SCHEMBL28869447

SCHEMBL28869447

C=CCc1c(N)c(S(=O)(=O)O)c(S(=O)(=O)O)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.35
DAPK1 P53355 1/20 0.34
CYP2D6 P10635 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 1/20 0.33
TTR P02766 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SUMO2 P61956 2/20 0.31
SUMO1 P63165 2/20 0.31
SENP7 Q9BQF6 2/20 0.31
SENP2 Q9HC62 2/20 0.31
SENP1 Q9P0U3 2/20 0.31
IMPDH2 P12268 1/20 0.31
SENP3 Q9H4L4 1/20 0.30
APP P05067 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11392963 0.88 DAPK1 (0.38) PDE4BDAPK1CYP2D6MEN1KMT2A
SCHEMBL27995034 0.86 PDE4B (0.37) PDE4BCYP2D6MEN1KMT2AKDM4E
SCHEMBL9401963 0.76 DAPK1 (0.43) DAPK1CYP2D6MEN1KMT2AKDM4E
SCHEMBL9287366 0.75 TTR (0.38) CYP2D6MEN1KMT2ATTRALDH1A1
SCHEMBL1244463 0.75 DAPK1 (0.42) DAPK1CYP2D6MEN1KMT2ATTR
SCHEMBL6526692 0.75 DAPK1 (0.42) DAPK1CYP2D6MEN1KMT2AKDM4E
SCHEMBL31552425 0.75 DAPK1 (0.42) DAPK1CYP2D6MEN1KMT2ATTR
SCHEMBL9706720 0.72 POLB (0.36) TDP1
SCHEMBL8379569 0.72 DAPK1 (0.47) DAPK1CYP2D6MEN1KMT2ATTR
SCHEMBL28220403 0.72 KDM4E (0.39) MEN1KMT2AKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105368452-B Silicon oxide layer etching solution 易安爱富科技有限公司 2019-02-19 CN disclosed