Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.74 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356588 | 0.84 | S1PR1 (0.65) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL6504714 | 0.84 | S1PR1 (0.65) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL16217982 | 0.84 | S1PR1 (0.65) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL2088387 | 0.84 | S1PR1 (0.65) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL16210711 | 0.83 | S1PR1 (0.63) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL28912728 | 0.81 | SIRT2 (0.71) | SIRT2S1PR1HDAC1HDAC2HDAC8 | |
| SCHEMBL19835706 | 0.81 | SIRT2 (0.70) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL27034970 | 0.81 | SIRT2 (0.61) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL203702 | 0.80 | S1PR1 (0.55) | SIRT2S1PR1S1PR3HDAC1HDAC2 | |
| SCHEMBL27034957 | 0.80 | S1PR1 (0.60) | SIRT2S1PR1S1PR3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |