Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15299292 | 0.84 | SIRT2 (0.64) | SIRT2TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10937283 | 0.84 | SIRT2 (0.71) | SIRT2TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10173253 | 0.84 | SMN1; SMN2 (0.59) | TDP1L3MBTL1HTTRAB9ANPC1 | |
| SCHEMBL201986 | 0.84 | SIRT2 (0.71) | SIRT2TDP1L3MBTL1HTTRAB9A | |
| SCHEMBL14788168 | 0.80 | SIRT2 (0.74) | SIRT2TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15287156 | 0.77 | SIRT2 (0.56) | SIRT2TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL22530395 | 0.77 | SIRT2 (0.56) | SIRT2TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12433084 | 0.76 | ERCC1 (0.55) | SIRT2NOTUM | |
| SCHEMBL6328232 | 0.76 | TSHR (0.74) | SIRT2RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL203702 | 0.76 | S1PR1 (0.55) | SIRT2TDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |