Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923020 | 0.85 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL28126221 | 0.85 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL28140845 | 0.84 | NPC1 (0.50) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27391382 | 0.83 | NPC1 (0.60) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27391381 | 0.83 | NPC1 (0.60) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL28130714 | 0.81 | MAPT (0.58) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL5313684 | 0.80 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27762381 | 0.80 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27409758 | 0.80 | NPC1 (0.60) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27409755 | 0.80 | NPC1 (0.60) | NPC1MAPTRAB9ALMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565449-B | A kind of preparation method and application for the chalcone compounds can increase cigarette smoking sweet tea sense | 云南中烟工业有限责任公司 | 2019-02-19 | — | — | CN | claimed |