Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435947 | 0.82 | GAA (0.47) | GAANOS3NOS2ITGB3ITGA2B | |
| SCHEMBL9382040 | 0.79 | F2 (0.44) | GAAF2CPN1CPB2TPSAB1 | |
| SCHEMBL9059898 | 0.79 | F2 (0.44) | GAAF2CPN1CPB2TPSAB1 | |
| SCHEMBL28851673 | 0.78 | GAA (0.42) | GAANOS3NOS2ITGB3ITGA2B | |
| SCHEMBL4572154 | 0.76 | MAPT (0.44) | GAANOS3NOS2 | |
| SCHEMBL17672505 | 0.76 | GAA (0.41) | GAANOS3NOS2CHRM1 | |
| SCHEMBL20900695 | 0.76 | CPN1 (0.47) | GAACPN1CPB2NOS3NOS2 | |
| SCHEMBL13245891 | 0.74 | EPHX2 (0.47) | GAA | |
| SCHEMBL24158928 | 0.74 | GAA (0.40) | GAATPSAB1TPSD1TPSG1NOS3 | |
| SCHEMBL15888619 | 0.74 | PIK3CA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415381-A | Thiazolopyridine derivatives as GPR119 agonist | 人类制药有限公司 | 2019-03-01 | — | — | CN | disclosed |