Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CCND1 | P24385 | 3/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870788 | 1.00 | CDK4 (0.55) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL11813801 | 0.80 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5820790 | 0.80 | CDK4 (0.70) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL29956738 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL335511 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL1307554 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL91201 | 0.79 | ERN1 (0.61) | MAPTLMNAGAASMN1; SMN2HSD11B1 | |
| SCHEMBL28278440 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL28266390 | 0.78 | ERN1 (0.59) | MAPTLMNAGAASMN1; SMN2HSD11B1 | |
| SCHEMBL28870804 | 0.77 | CDK4 (0.55) | CDK4CCND1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |