SCHEMBL2887128

SCHEMBL2887128

O=C1N=C2NC(=O)NC2N1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11352404 0.51 TSHR (0.46) TSHR
SCHEMBL14026567 0.51
SCHEMBL13954334 0.51
SCHEMBL14354358 0.51 TSHR (0.52) TSHR
SCHEMBL976613 0.48
SCHEMBL21767 0.48
SCHEMBL1362681 0.48
SCHEMBL437096 0.48
SCHEMBL8110002 0.48
SCHEMBL8997547 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393973-A1 LOW EMISSION PHENOLIC RESINS Prefere Resins Holding GmbH (DE) 2024-07-03 EP claimed
CN-116171302-A Antimicrobial coating PPG建筑涂层有限公司 2023-05-26 CN claimed
US-11344857-B2 Microcapsules SYMRISE AG (DE) 2022-05-31 US claimed
EP-3558508-B1 MICROCAPSULES SYMRISE AG (DE) 2022-03-30 EP claimed
US-20090088483-A1 AQUEOUS SUSPENSIONS OR DISPERSIONS OF INORGANIC PIGMENTS CONTAINING A MIXTURE CONSISTING OF DIALDEHYDES AND FORMALDEHYDE CLEAVERS ISP INVESTMENTS INC. 2009-04-02 US claimed
EP-4321569-B1 FLAME-RETARDANT CROSSLINKED ALIPHATIC POLYKETONES FREUDENBERG CARL KG (DE) 2025-03-26 EP disclosed
EP-4393973-A1 LOW EMISSION PHENOLIC RESINS Prefere Resins Holding GmbH (DE) 2024-07-03 EP disclosed
WO-2024116551-A1 PHOTOCURABLE COMPOSITION パナソニックIPマネジメント株式会社 2024-06-06 WO disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
US-20240066778-A1 FLAME-RETARDANT CROSSLINKED ALIPHATIC POLYKETONES CARL FREUDENBERG KG (DE) 2024-02-29 US disclosed
CN-117586602-A Flame-retardant molded article for electrical devices 科德宝两合公司 2024-02-23 CN disclosed
CN-117586603-A Flame-retardant crosslinked aliphatic polyketones 科德宝两合公司 2024-02-23 CN disclosed
WO-2008136842-A1 POLY( CARBONATE-CO-UREA) COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-13 WO disclosed
US-20080275206-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-7205316-B2 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands ABBOTT LABORATORIES (US) 2007-04-17 US disclosed
EP-1751130-A2 TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2007-02-14 EP disclosed
US-20050272736-A1 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands ABBVIE INC. 2005-12-08 US disclosed
WO-2005113536-A2 TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2005-12-01 WO disclosed
US-20050256309-A1 Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands ABBOTT LABORATORIES 2005-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050272736-A1 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands HRH3, HRH4, HRH2 TSHR 84/4885PDE3B 2052/4885PDE3A 1918/4885
US-20050256309-A1 Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands HRH3, HRH4, HRH2 TSHR 84/4885PDE3B 2052/4885PDE3A 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.