Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559747 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL17478640 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL11102795 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL17478643 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3928569 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL2855312 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL17478873 | 0.78 | GAA (0.65) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL14226837 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL3931220 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAKDM4EALDH1A1HPGD | |
| SCHEMBL28923681 | 0.77 | GAA (0.58) | SMN1; SMN2GAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678815-B | N-benzyl benzamide derivative and preparation method and pharmaceutical application thereof | 中国药科大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-109678815-A | N- benzyl benzamide derivatives and preparation method thereof and pharmaceutical applications | 中国药科大学 | 2019-04-26 | — | — | CN | disclosed |