Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC15A1 | P46059 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155008 | 1.00 | ALPI (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8610379 | 0.85 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL21553135 | 0.85 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6523945 | 0.85 | SLC7A5 (0.57) | SLC7A5HDAC8 | |
| SCHEMBL168029 | 0.85 | SLC7A5 (0.57) | SLC7A5HDAC8 | |
| SCHEMBL3476198 | 0.84 | SLC7A5 (0.56) | SLC7A5HDAC8 | |
| SCHEMBL27746572 | 0.84 | ALPI (0.54) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27831833 | 0.84 | ALPI (0.54) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Methyl Ester SCHEMBL14988957 | 0.83 | MEN1 (0.57) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2785098 | 0.82 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119410678-A | Method for optimizing antibody expression | AMBRX公司 | 2025-02-11 | — | — | CN | claimed |
| CN-112313336-B | Method for optimizing antibody expression | AMBRX公司 | 2024-12-03 | — | — | CN | claimed |
| CN-117924503-A | Humanized anti-Prostate Specific Membrane Antigen (PSMA) antibody drug conjugates | AMBRX公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115243726-A | Interleukin-2 polypeptide conjugates and methods of use thereof | 北京泰德制药股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-119410678-A | Method for optimizing antibody expression | AMBRX公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119410679-A | Method for optimizing antibody expression | AMBRX公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-117924503-A | Humanized anti-Prostate Specific Membrane Antigen (PSMA) antibody drug conjugates | AMBRX公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117286182-A | Methods and compositions for promoting production of proteins containing unnatural amino acids | AMBRX公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-110959041-B | Methods and compositions for promoting production of proteins containing unnatural amino acids | AMBRX公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115243726-A | Interleukin-2 polypeptide conjugates and methods of use thereof | 北京泰德制药股份有限公司 | 2022-10-25 | — | — | CN | disclosed |