SCHEMBL28872400

SCHEMBL28872400

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3.[SiH4].[Zn]

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.40
▸ STAT1 P42224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738113 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL28973498 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL78009 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL7738107 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL30555931 0.95 STAT3 (0.40) STAT3STAT1
Hydrochloric Acid SCHEMBL11327619 0.95 STAT3 (0.40) STAT3STAT1
Ammonia Solution, Strong SCHEMBL28670113 0.95 STAT3 (0.40) STAT3STAT1
Iodide SCHEMBL11328134 0.95 STAT3 (0.40) STAT3STAT1
Phosphine SCHEMBL29118238 0.95 STAT3 (0.40) STAT3STAT1
SCHEMBL29560791 0.95 STAT3 (0.40) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114209826-B Zinc porphyrin nanoparticle for tumor photo-thermal photodynamic combined treatment 中国科学院苏州生物医学工程技术研究所 2023-05-12 — — CN claimed
CN-114209826-A Zinc porphyrin nano-particle for tumor photothermal and photodynamic combined treatment 中国科学院苏州生物医学工程技术研究所 2022-03-22 — — CN claimed
CN-114209826-B Zinc porphyrin nanoparticle for tumor photo-thermal photodynamic combined treatment 中国科学院苏州生物医学工程技术研究所 2023-05-12 — — CN disclosed
CN-114209826-A Zinc porphyrin nano-particle for tumor photothermal and photodynamic combined treatment 中国科学院苏州生物医学工程技术研究所 2022-03-22 — — CN disclosed
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