Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698277 | 0.82 | KMT2A (0.58) | KMT2AEPHX2NR1H4ALDH1A1HSD17B10 | |
| SCHEMBL29613624 | 0.79 | CYP19A1 (0.47) | KMT2ALMNAALDH1A1RAB9APOLB | |
| SCHEMBL24510728 | 0.78 | KMT2A (0.61) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL19422110 | 0.78 | KMT2A (0.61) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL10131958 | 0.78 | KMT2A (0.68) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL5987974 | 0.76 | KMT2A (0.75) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL18601990 | 0.76 | KMT2A (0.59) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL23659579 | 0.76 | KMT2A (0.74) | KMT2AEPHX2NR1H4LMNAALDH1A1 | |
| SCHEMBL15840092 | 0.75 | SMN1; SMN2 (0.46) | KMT2ALMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL334751 | 0.74 | KMT2A (0.70) | KMT2ALMNAALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143886-B | Process for the preparation of beta-arylaminoalkols such as tulobuterol, chlorpropaline, isoadrenaline dichloride and sotalol | 北京化工大学 | 2022-11-01 | — | — | CN | disclosed |