Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12580619 | 1.00 | ABCB1 (0.39) | ABCB1KCNA5TAAR1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL2888939 | 0.99 | ABCB1 (0.38) | ABCB1KCNA5TAAR1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL2888940 | 0.99 | ABCB1 (0.38) | ABCB1KCNA5TAAR1CHRM2CHRM1 | |
| SCHEMBL2007669 | 0.85 | ABCB1 (0.48) | ABCB1KCNA5 | |
| SCHEMBL2888894 | 0.85 | ABCB1 (0.48) | ABCB1KCNA5 | |
| SCHEMBL2888796 | 0.84 | ABCB1 (0.41) | ABCB1KCNA5TAAR1CHRM2CHRM1 | |
| SCHEMBL2875861 | 0.84 | ABCB1 (0.41) | ABCB1KCNA5TAAR1CHRM2CHRM1 | |
| SCHEMBL2888729 | 0.83 | NPC1 (0.42) | ABCB1KCNA5TAAR1NPC1RAB9A | |
| SCHEMBL2888730 | 0.83 | NPC1 (0.42) | ABCB1KCNA5TAAR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2883776 | 0.82 | NPC1 (0.41) | ABCB1KCNA5TAAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | claimed |