Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264849 | 0.98 | HTR2A (0.54) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| SCHEMBL11343665 | 0.98 | HTR2A (0.54) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| SCHEMBL11343335 | 0.98 | HTR2A (0.54) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Hydrochloric Acid SCHEMBL10483838 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Bromide SCHEMBL9421740 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Hydrochloric Acid SCHEMBL28264791 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Hydrochloric Acid SCHEMBL10939857 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Hydrochloric Acid SCHEMBL11782326 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| Hydrochloric Acid SCHEMBL9392600 | 0.96 | HTR2A (0.53) | HTR2AGABBR2GABBR1TAAR1HRH1 | |
| SCHEMBL4948330 | 0.94 | HTR2A (0.49) | HTR2AGABBR2GABBR1TAAR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912467-A | A kind of synthetic method of 2- aryl phenylethylamine derivative | 南昌航空大学 | 2019-06-21 | — | — | CN | claimed |
| CN-109912467-A | A kind of synthetic method of 2- aryl phenylethylamine derivative | 南昌航空大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912467-A | A kind of synthetic method of 2- aryl phenylethylamine derivative | 南昌航空大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912467-A | A kind of synthetic method of 2- aryl phenylethylamine derivative | 南昌航空大学 | 2019-06-21 | — | — | CN | disclosed |