Dimethylformamide

Dimethylformamide

SCHEMBL28873647

CN(C)C=O.CN(C)C=O.N

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.90
TAS2R38 P59533 1/20 0.36
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
USP2 O75604 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL21436169 1.00
Dimethylformamide SCHEMBL27556220 1.00 TSHR (0.90) TSHRTAS2R38ADH1CADH1AUSP2
Dimethylformamide SCHEMBL28155944 1.00 TSHR (0.90) TSHRTAS2R38ADH1CADH1AUSP2
Dimethylformamide SCHEMBL5808716 1.00
Dimethylformamide SCHEMBL28098690 0.95
Dimethylformamide SCHEMBL28292810 0.95
Dimethylformamide SCHEMBL1927321 0.95 TSHR (1.00) TSHRTAS2R38ADH1CADH1AUSP2
Dimethylformamide SCHEMBL10141201 0.95
Dimethylformamide SCHEMBL5 0.95
Dimethylformamide SCHEMBL2280000 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103434-B Tetrahydropyridine and pyrimidine compound or its salt 大鹏药品工业株式会社 2019-05-10 CN disclosed