SCHEMBL2887376

SCHEMBL2887376

CCCCC(CC)c1cccs1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CTSK P43235 1/20 0.35
HDAC3 O15379 1/20 0.34
NR1I2 O75469 1/20 0.34
ALOX5 P09917 1/20 0.33
HSPA5 P11021 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KEAP1 Q14145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598926 0.95 KDM4E (0.40) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL5402599 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL5415617 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL2888749 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL2494816 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL11893297 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL8411841 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL1422000 0.93 NR1I2 (0.42) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL16334692 0.89 GLA (0.39) KDM4EGLATSHRHTTL3MBTL1
SCHEMBL20372967 0.89 GLA (0.39) KDM4EGLATSHRHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230043959-A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS INCYTE CORPORATION 2023-02-09 US disclosed
EP-4027353-A1 CONDUCTIVE MATERIAL AND SUBSTRATE Shin-Etsu Chemical Co., Ltd. (JP) 2022-07-13 EP disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 EP disclosed
EP-3067897-B1 CONDUCTIVE MATERIAL AND SUBSTRATE SHINETSU CHEMICAL CO (JP) 2020-05-27 EP disclosed
US-10563071-B2 Method for producing conductive polymer-containing dispersion SHOWA DENKO K.K. (JP) 2020-02-18 US disclosed
US-10563020-B2 Process for producing dispersion containing electroconductive polymer SHOWA DENKO K.K. (JP) 2020-02-18 US disclosed
CN-110249006-A Conductive composition, method for producing conductive composition, and method for producing electrical conductor 三菱化学株式会社 2019-09-17 CN disclosed
CN-110119075-A Toner, image forming apparatus and image forming method 京瓷办公信息系统株式会社 2019-08-13 CN disclosed
EP-3073494-B1 CONDUCTIVE MATERIAL AND SUBSTRATE SHINETSU CHEMICAL CO (JP) 2019-06-26 EP disclosed
US-10305063-B2 Transparent organic electroluminescence element Konica Minolta, Inc. (JP) 2019-05-28 US disclosed
CN-101035860-A Conductive composition and method for producing same, antistatic coating, antistatic film, optical filter, optical information recording medium, and capacitor and method for producing same SHINETSU POLYMER CO (JP) 2007-09-12 CN disclosed
CN-101023138-A Conductive composition and process for production thereof, antistatic coating material, antistatic membrane, antistatic film, optical filter, optical information recording media, and condenser and pro SHINETSU POLYMER CO (JP) 2007-08-22 CN disclosed
CN-1856523-A Pi-conjugated copolymer production method thereof and capacitor using the copolymer SHOWA DENKO KK (JP) 2006-11-01 CN disclosed
CN-1806005-A Conductive composition, conductive coating material, conductive resin, capacitor, photoelectric conversion element, and method for producing same SHINETSU POLYMER CO (JP) 2006-07-19 CN disclosed
CN-1795580-A Electrolyte composition and photoelectric conversion element using same FUJIKURA LTD (JP) 2006-06-28 CN disclosed
CN-1714417-A Solid electrolytic capacitor and method for manufacturing the same SHOWA DENKO KK (JP) 2005-12-28 CN disclosed
CN-1679125-A Metal foil for capacitor, solid electrolytic capacitor using the same, and method for producing foil and capacitor SHOWA DENKO KK (JP) 2005-10-05 CN disclosed
CN-1193057-C Conductive polymer, solid electrolytic capacitor and process for producing these SHOWA DENKO KK (JP) 2005-03-16 CN disclosed
CN-1516883-A Formed substrate used for solide electrolytic capacitor, production method and solid electrolytic capacitor using substrate �Ѻ͵繤��ʽ���� 2004-07-28 CN disclosed
CN-1273677-A Conductive polymer, solid electrolytic capacitor and process for producing these SHOWA DENKO KK (JP) 2000-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043959-A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS JAK1, JAK2, JAK3 KDM4E 347/4885GLA 4826/4885TSHR 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.