Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16008 | 0.97 | TSHR (0.50) | TSHRHPGDPRKCAPRKCDTHRB | |
| Ethylene Glycol SCHEMBL5144202 | 0.95 | TSHR (0.46) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL6046850 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| Ethylene SCHEMBL16225793 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL29186353 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL4418169 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL665164 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL3800763 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL11460175 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB | |
| SCHEMBL28019911 | 0.95 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971019-A | A kind of elastomer and its preparation method and application of the super lubrication high transparency in surface | 苏州凝智新材料发展有限公司 | 2019-07-05 | — | — | CN | disclosed |