SCHEMBL2887448

SCHEMBL2887448

O=C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NC[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.35
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20746294 0.86 GBA1 (0.38) GBA1
SCHEMBL22028085 0.84 GBA1 (0.37) GBA1
SCHEMBL20745887 0.84 GBA1 (0.37) GBA1
SCHEMBL1234198 0.82 GBA1 (0.39) GBA1
SCHEMBL20746034 0.77 GBA1 (0.32) GBA1
SCHEMBL22738553 0.74 KDM4E (0.44) KDM4E
SCHEMBL22738592 0.74 KDM4E (0.44) KDM4E
SCHEMBL26534077 0.71 KDM4E (0.47) KDM4E
SCHEMBL1235601 0.70 GBA1 (0.44) GBA1
SCHEMBL8088030 0.70 GBA1 (0.50) GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102650-B1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AGENCY SCIENCE TECH & RES (SG) 2021-05-19 EP disclosed
US-20170307486-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY SCIENCE TECH & RES (SG) 2017-10-26 US disclosed
US-9581527-B2 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-02-28 US disclosed
US-20140234873-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-08-21 US disclosed
EP-2004328-B1 METHOD FOR PERFORMING A REACTION IN A DROPLET AGENCY SCIENCE TECH & RES (SG) 2014-06-04 EP disclosed
US-20130236377-A1 APPARATUS FOR PERFORMING A REACTION IN A DROPLET AND METHOD OF USING THE SAME KIM NAM YONG (US) 2013-09-12 US disclosed
US-8261598-B2 Apparatus for performing a reaction in a droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-09-11 US disclosed
US-20100285573-A1 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-11 US disclosed
US-20100000304-A1 Apparatus For Performing a Reaction In a Droplet and Method of Using the Same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2010-01-07 US disclosed
EP-2102650-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME Agency for Science, Technology And Research (SG) 2009-09-23 EP disclosed
EP-2004328-A4 APPARATUS FOR PERFORMING A REACTION IN A DROPLET AND METHOD OF USING THE SAME AGENCY SCIENCE TECH & RES (SG) 2009-07-22 EP disclosed
EP-2004328-A1 APPARATUS FOR PERFORMING A REACTION IN A DROPLET AND METHOD OF USING THE SAME Agency for Science, Technology and Research (SG) 2008-12-24 EP disclosed
WO-2008063135-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed
WO-2008063136-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed
WO-2007102785-A1 APPARATUS FOR PERFORMING A REACTION IN A DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2007-09-13 WO disclosed