SCHEMBL28875736

SCHEMBL28875736

O=[N+]([O-])c1ccc(O)c(Cl)c1.[Hg].[Hg]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.64
ALDH1A1 P00352 6/20 0.60
GPR35 Q9HC97 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
HPGD P15428 2/20 0.60
TP53 P04637 2/20 0.60
TSHR P16473 2/20 0.60
MAPK1 P28482 2/20 0.60
GAA P10253 2/20 0.58
THRB P10828 1/20 0.58
KMT2A Q03164 3/20 0.56
ERN1 O75460 1/20 0.55
MEN1 O00255 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
AURKA O14965 1/20 0.52
NPC1 O15118 1/20 0.52
PDPK1 O15530 1/20 0.52
JAK2 O60674 1/20 0.52
GMNN O75496 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27467381 1.00 HSD17B10 (0.64) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
SCHEMBL140502 0.98 HSD17B10 (0.67) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
Potassium Ion SCHEMBL14353304 0.96 HSD17B10 (0.64) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
SCHEMBL14353306 0.96 HSD17B10 (0.64) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
Methoxymethane SCHEMBL28737078 0.91 HSD17B10 (0.58) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
P-Nitrophenol SCHEMBL28539749 0.91 HSD17B10 (0.58) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
Piperazine SCHEMBL10789667 0.88 HSD17B10 (0.55) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
Piperazine SCHEMBL10789670 0.88 HSD17B10 (0.55) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
SCHEMBL8824221 0.86 HSD17B10 (0.53) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD
4-Chloro-Benzoic Acid SCHEMBL28231535 0.84 TDP1 (0.56) HSD17B10ALDH1A1GPR35SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234349-A Specifically combine the antibody and application thereof of human IL-15 赛福伦公司 2019-09-13 CN disclosed