Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.57 |
| ▸ | CDK2 | P24941 | 6/20 | 0.57 |
| ▸ | CDK9 | P50750 | 6/20 | 0.57 |
| ▸ | SYK | P43405 | 2/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | BTK | Q06187 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463618 | 1.00 | BRD4 (0.59) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL28714151 | 0.92 | FLT3 (0.59) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL29514559 | 0.92 | FLT3 (0.59) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL28876155 | 0.92 | SYK (0.69) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL29463619 | 0.92 | SYK (0.69) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL29463626 | 0.91 | BRD4 (0.72) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL28876170 | 0.91 | BRD4 (0.72) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL28876165 | 0.90 | BRD4 (0.65) | BRD4SYKGSK3AGSK3BHDAC3 | |
| SCHEMBL29463622 | 0.89 | BRD4 (0.59) | BRD4CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL28876153 | 0.89 | BRD4 (0.59) | BRD4CCNT1CCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230524-A | (5-fluoro-2-anilinopyrimidin-4-yl) amino-N-hydroxybenzamide derivative and preparation method and application thereof | 南通大学 | 2022-03-25 | — | — | CN | claimed |
| CN-114230524-A | (5-fluoro-2-anilinopyrimidin-4-yl) amino-N-hydroxybenzamide derivative and preparation method and application thereof | 南通大学 | 2022-03-25 | — | — | CN | disclosed |