Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL27892029 | 0.92 | TP53 (0.55) | TP53RNPEPCYP1A2ENPEPSMN1; SMN2 | |
| Lactic Acid SCHEMBL11684316 | 0.90 | TP53 (0.52) | TP53RNPEPCYP1A2ENPEPSMN1; SMN2 | |
| Thioglycolic Acid SCHEMBL5074469 | 0.88 | TP53 (0.44) | TP53RNPEPCYP1A2ENPEP | |
| Thioglycolic Acid SCHEMBL110271 | 0.88 | — | — | |
| Thioglycolic Acid SCHEMBL27952872 | 0.86 | TP53 (0.45) | TP53RNPEPCYP1A2ENPEPSMN1; SMN2 | |
| Thioglycolic Acid SCHEMBL9482863 | 0.86 | TP53 (0.45) | TP53RNPEPCYP1A2ENPEP | |
| Thioglycolic Acid SCHEMBL4528557 | 0.85 | — | — | |
| Thioglycolic Acid SCHEMBL9482875 | 0.83 | TP53 (0.43) | TP53RNPEPCYP1A2ENPEP | |
| Thioglycolic Acid SCHEMBL9420753 | 0.82 | ACE (0.46) | TP53RNPEPCYP1A2ENPEPFOLH1 | |
| Thioglycolic Acid SCHEMBL2021002 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261872-A | Rust remover for steel parts and preparation method thereof | 上海丽卡环保技术有限公司 | 2022-11-01 | — | — | CN | disclosed |