Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.74 |
| ▸ | RAB9A | P51151 | 10/20 | 0.74 |
| ▸ | STAT1 | P42224 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | ALPL | P05186 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ACP1 | P24666 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973978 | 1.00 | NPC1 (0.74) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL18585932 | 0.87 | NPC1 (0.77) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL6057541 | 0.85 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL23629012 | 0.84 | NPC1 (0.75) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL4746072 | 0.82 | NPC1 (0.77) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL14808429 | 0.82 | SMN1; SMN2 (0.77) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL11303998 | 0.82 | NPC1 (0.80) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL1094691 | 0.82 | NPC1 (0.65) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL4667327 | 0.81 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E | |
| SCHEMBL145671 | 0.80 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9ASTAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151536-A | Antiviral compounds, compositions and methods of use | 不列颠哥伦比亚大学 | 2022-10-04 | — | — | CN | disclosed |