Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SCNN1A | P37088 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239111 | 1.00 | CTSA (0.52) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL28329413 | 1.00 | CTSA (0.52) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17101408 | 0.86 | CTSA (0.53) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17101459 | 0.86 | CTSA (0.51) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17101233 | 0.86 | CTSA (0.51) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17101195 | 0.86 | CTSA (0.51) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17101507 | 0.82 | CTSA (0.47) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17108621 | 0.80 | CTSA (0.46) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17108624 | 0.80 | CTSA (0.46) | CTSAGRM5SCNN1AALDH1A1KDM4E | |
| SCHEMBL17108605 | 0.80 | CTSA (0.44) | CTSAGRM5SCNN1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103423-B | Pyrazine compounds | 阿斯利康(瑞典)有限公司 | 2019-12-06 | — | — | CN | disclosed |