Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.51 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410469 | 0.88 | GRIA1 (0.52) | MAPK14RIPK3ALOX5FAAHMAPK13 | |
| SCHEMBL25043409 | 0.86 | RIPK3 (0.52) | MAPK14RIPK3ALOX5FAAHMAPK13 | |
| SCHEMBL23410499 | 0.78 | MAPK14 (0.53) | MAPK14RIPK3ALOX5MAPK13MAPK12 | |
| SCHEMBL23410552 | 0.77 | GRIA1 (0.51) | MAPK14RIPK3MAPK13MAPK12MAPK11 | |
| SCHEMBL28878621 | 0.77 | MAPK14 (0.49) | MAPK14RIPK3MAPK13MAPK12MAPK11 | |
| SCHEMBL23410401 | 0.77 | GRIA1 (0.53) | MAPK14RIPK3 | |
| SCHEMBL23410636 | 0.76 | GRIA1 (0.50) | MAPK14RIPK3MAPK13MAPK12MAPK11 | |
| SCHEMBL30232556 | 0.74 | RIPK3 (0.50) | MAPK14RIPK3MAPK13MAPK12MAPK11 | |
| SCHEMBL25044591 | 0.74 | RIPK3 (0.52) | MAPK14RIPK3MAPK13MAPK12MAPK11 | |
| SCHEMBL30232366 | 0.74 | RIPK3 (0.49) | MAPK14RIPK3MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151256-A | Novel compounds for the treatment of diseases associated with DUX expression | FACIO知识产权有限公司 | 2022-10-04 | — | — | CN | disclosed |