Benzene

Benzene

SCHEMBL28879586

Oc1ccsc1.c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2B6 P20813 1/20 0.46
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
DAO P14920 1/20 0.44
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GLA P06280 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA9 Q16790 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
HPGD P15428 1/20 0.38
ADRA2A P08913 2/20 0.36
ADRA2B P18089 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133671 0.94
SCHEMBL28211733 0.91
SCHEMBL11525247 0.91
SCHEMBL29350098 0.91
SCHEMBL30834636 0.91
Methane SCHEMBL510551 0.91
Biphenyl SCHEMBL28335911 0.90 CYP2A6 (0.62) CYP2E1CYP2A6CYP2B6LCKFYN
Ethane SCHEMBL1300586 0.88
Ethylene SCHEMBL27723901 0.88
Ethyne SCHEMBL29270247 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110441460-A Minigene toxic impurities detection method in a kind of voriconazole WUHAN LANGLAI TECH DEVELOPMENT CO LTD 2019-11-12 CN disclosed