Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730613 | 0.81 | BRD4 (0.54) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16868381 | 0.79 | BRD4 (0.58) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16660689 | 0.79 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16333294 | 0.78 | BRD4 (0.57) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL20159992 | 0.78 | BRD4 (0.57) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16658392 | 0.76 | BRD4 (0.55) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16651491 | 0.76 | BRD4 (0.55) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16651036 | 0.74 | BRD4 (0.48) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL20160100 | 0.72 | BRD4 (0.60) | BRD4EP300BRD2ADORA2BTSPO | |
| SCHEMBL16335743 | 0.72 | BRD4 (0.59) | BRD4EP300BRD2ADORA2BTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558889-B | Bromodomain inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-105828820-B | Bromodomain inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-01-07 | — | — | CN | disclosed |