Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3419151 | 1.00 | OPRL1 (0.49) | OPRL1MITFMAPTHTTPREP | |
| SCHEMBL2072837 | 0.88 | NPSR1 (0.54) | MITFMAPTHTTPREPNPSR1 | |
| SCHEMBL13259971 | 0.87 | MEN1 (0.49) | OPRL1PREPNPSR1MEN1KMT2A | |
| SCHEMBL3148090 | 0.87 | MEN1 (0.51) | OPRL1PREPNPSR1MEN1KMT2A | |
| SCHEMBL628051 | 0.87 | MEN1 (0.51) | OPRL1PREPNPSR1MEN1KMT2A | |
| SCHEMBL628052 | 0.87 | MEN1 (0.51) | OPRL1PREPNPSR1MEN1KMT2A | |
| SCHEMBL1864842 | 0.83 | POLB (0.52) | MITFMAPTHTTPREPNPSR1 | |
| SCHEMBL7802196 | 0.83 | POLB (0.52) | MITFMAPTHTTPREPNPSR1 | |
| SCHEMBL2300448 | 0.83 | POLB (0.52) | MITFMAPTHTTPREPNPSR1 | |
| SCHEMBL15307912 | 0.82 | HTR2C (0.56) | PREPNPSR1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727407-B | Novel benzodiazepine derivatives | 伊缪诺金公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-105198908-B | Novel benzodiazepine derivatives | 伊缪诺金公司 | 2019-12-24 | — | — | CN | disclosed |