Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18420648 | 0.72 | MEN1 (0.40) | MAPTGALR3KDM4EMEN1HPGD | |
| SCHEMBL8280362 | 0.70 | GALR3 (0.38) | MAPTGALR3KDM4ETSHRKMT2A | |
| SCHEMBL29076355 | 0.70 | PIM1 (0.32) | MAPTGALR3 | |
| SCHEMBL29277393 | 0.70 | MAPT (0.32) | MAPTGALR3CYP1A2CYP2C19 | |
| SCHEMBL8150180 | 0.70 | CCNE2 (0.38) | MAPTGALR3MEN1CYP3A4KMT2A | |
| SCHEMBL11028700 | 0.69 | MAPT (0.36) | MAPTGALR3KDM4E | |
| SCHEMBL2929885 | 0.69 | MAPT (0.41) | MAPTGALR3KDM4EMEN1CYP1A2 | |
| SCHEMBL29030024 | 0.69 | DYRK1A (0.42) | MAPTADORA2AADORA2BKDM4EMEN1 | |
| SCHEMBL30537728 | 0.69 | PIM1 (0.31) | MAPT | |
| SCHEMBL29076262 | 0.69 | PIM1 (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110606851-A | Insensitive high-energy energetic compound with excellent thermal stability and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2019-12-24 | — | — | CN | claimed |
| CN-110606851-A | Insensitive high-energy energetic compound with excellent thermal stability and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2019-12-24 | — | — | CN | disclosed |