Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.40 |
| ▸ | ATR | Q13535 | 3/20 | 0.39 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.37 |
| ▸ | RICTOR | Q6R327 | 5/20 | 0.37 |
| ▸ | MAPKAP1 | Q9BPZ7 | 5/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811121 | 0.81 | ATR (0.57) | MTORPIK3CAPIK3R1ATRPIK3CD | |
| SCHEMBL1180995 | 0.81 | ATR (0.57) | MTORPIK3CAPIK3R1ATRPIK3CD | |
| SCHEMBL1180994 | 0.81 | ATR (0.57) | MTORPIK3CAPIK3R1ATRPIK3CD | |
| SCHEMBL1182984 | 0.80 | MTOR (0.47) | MTORPIK3CAPIK3R1ATRRPTOR | |
| SCHEMBL1182986 | 0.80 | MTOR (0.47) | MTORPIK3CAPIK3R1ATRRPTOR | |
| SCHEMBL29805712 | 0.80 | MTOR (0.48) | MTORPIK3CAPIK3R1ATRRPTOR | |
| SCHEMBL4443778 | 0.77 | MTOR (0.67) | MTORPIK3CAPIK3R1 | |
| SCHEMBL4443774 | 0.77 | MTOR (0.67) | MTORPIK3CAPIK3R1 | |
| SCHEMBL11813458 | 0.77 | MTOR (0.46) | MTOR | |
| SCHEMBL29805762 | 0.76 | ATR (0.47) | MTORATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |